If the NFL, like Madden, didn't allow subs when going no huddle, do you think teams would utilize the entire playbook, regardless of the personnel on the field? For example, if a real NFL team went no huddle from the I form, do you think they would audible into a 4 WR 1 RB Shotgun formation, using I form personnel?
Even the plays Senator Palmer was referring to are actual plays with specific personnel packages, not audible adjustments at the LOS using whatever personnel are out there at the time.
What I am saying and I think CR is too, is that no huddle audibles in Madden should be limited to the original plays formations/personnel. Teams should not be audibling into plays with different personnel packages, without that personnel being on the field.