Be sure to use your Wildcards "wisely". The advice I was given was to play on Arena for awhile to get used to the interface, game, etc. Then start to do some drafts (if interested). I'm planning to do a few this weekend since Guilds of Ravnica just started back up in the Quick Draft format.
Only then should you consider using the Wildcards as you start to build a deck to play with in Constructed. You can then use the wildcards to fill in any gaps, or to select the Mythic/Rare that the rest of your cards can support.
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