As mentioned before you have to rush at least 4 if not 5 on obvious passing downs. A dime 3-2-6 with no blitz will get eaten alive because of no pressure.
Next, you'll have to manually patrol the middle of the field. Look at the formation if it's 3 WR to one side, cheat over there with an MLB because the guy going over the middle is likely coming from this side. If WR's are balanced, watch the slot WR's as one of them is likely running a post or seam route. Cover that guy manually with your zone defender. It makes the CPU QB go to their second read and buys your blitz some time to get pressure. Cover 3 works if you manually take away the middle. Man with cover-1 (safety and MLB in zone all others in man) is also good to throw in as is dime cover 3 man (cover 3 zone with man coverage on the slot WR) all these can help take the deep middle away which is where the CPU loves to go on third and long. Also if its over 3rd and 13 I'll run Dime 3-2-6 cover 4 to be safe. You get no pass rush here but because the CPU has to go 13 yards, the cover 4 is effective at shutting down the deep middle. One more tip, if you have fast DE's, audible them wide and to the outside rush, they seem to get better pressure this way.
Plus with adaptive AI I think you have to mix your coverages. As mentioned above I alternate between Cover 3, Cover 1 man, and Dime Cover 3 / Man. I also vary the blitzes from Dime and Dime 3-2-6 and if I'm really getting torched, I'll switch to Nickle 3-3-5 blitzes.
The key is getting comfortable covering the receiver going deep up the middle with your player to make the QB go to his next read.