One thing Meyer did at Utah (and maybe at Bowling Green) was really effective meshing of Strong/Weak Offset I formations into the spread attack. Most teams struggle when they get too multiple, but the blocking assignments and WR alignment were almost exactly the same just with a FB/HBack moving from a wing to the Offset FB position.
I remember they used to run a Pro Right/Twins Right combo (Strong I Normal/Strong I Twins in NCAA terms). When they went Twins Right, they would motion the QB out of the backfield opposite of the Twins side, basically making a Wildcat formation. Then they had a Power/Counter/Pass series off of this. It is SUCH a deadly series because you take a defender away from a gap to account for the split QB and then you are lead blocking a FB, pulling guard and TE in front of a direct snap HB. Deadly.
I can see him going back to that. His final year at Florida, they had always talked about getting a bit more smashmouth to take the load of the new QB. It is still going to be mostly spread and option based, but the power/counter/trap game they run from the gun is easily accessible under center and may match OSU's personnel a bit better, at least for the first year or two.
I'm excited to see what he does there. Urban Meyer is one of my favorite coaches in football.