Yep, turns out that was the issue. I moved Lewis to Oklahoma State entirely and LSU was able to play games. Glad that the editor is around to be able to fix a glitch like that, it's weird that it developed even without me having previously edited anything in the dynasty.
Glad you found the answer. I experienced something similar when I wanted to watch my former OC's game. It turns out that I gave him my custom playbook when he was my OC and it fails to load for CPU controlled teams.