Pitcher Fatigue-55(this usually has me coming out in the 6th inning on average with my stamina at 79,may have to raise it as stamina goes up and the only way your goin a CG is if you give up 1 or fewer runs or throw very few pitches)
Batting CPU
45-50 contact(depends on how good your pitcher/you are)
100 power
Pitching HUM
pitch meter speed 100
pitch speed 100
pitch break influence 40
pitcher composure influence 100
Fielding AI
AI fielder speed 50(VERY IMPORTANT)
Baserunning AI (in order)
80
100
40
60
60
The other sliders are your choice and dont affect a pitcher in My Player mode very much.These sliders have given me great results and you will not be getting you ERA under 3.00 very easily with these.
Another suggestion i have is using PITCHING CAM1 1-7-5.This view makes the game look realistic but also will make it ALOT harder to hit your spots due to the strike zone looking much smaller and the position of it makes it so that its not exactly clear where the corners of the zone are.You will get walks occasionly but not to a realistic amount,but it will make you run deeper into counts alot more often so that your not goin 0-2 on every batter.