Are the CPU teams set such that a starter is listed as the second string to another position on the line? i had this happen through the season, thought I finally resolved it then had it happen again late in a playoff game. The thing I noticed was green bay (offending team) had only 8 offensive linemen, so players who were gassed were the natural replacement for another player who was gassed. After that I made sure teams had second stringers who were not starters and in the remaining few games did not have serial false starts. I also brought the FS slider to 50 so it may be one or the other or a combo that helped me.