I play all madden vs the cpu and hardly ever run man. The odds that 4 or 5 vastly superior receivers will all be covered on a given play are too low. Also the cpu instantly knows who's open, not needing to go through a read sequence. The last straw is the speed boost. If a slower wr gets half a step on your cb it will still be able to outrun the cb after the catch for huge rac.
I find the user pass rush pretty useless. I rarely blitz either, as the cpu instantly knows who's open and has super fast throwing release time.
So I usually play zone with 3 or 4 rushing