You can check my thread (mjhyankees modified Jdseven sliders). I also have some discussion on what i"m finding with these sliders and how i"m adjusting. basically the more you play the better you get and you have to help the cpu more and more over time.
Those sliders on that thread give me the best game consistently. I've played the same games (Bears-Packers and Jets- Bills) over an over with about 5-6 different slider sets. I find the other sliders give both sides and unstoppable passing game (unless human QB acc is below 20- then I have to throw short all day) and no running game.
Everytime I play I'm finding my modified sliders give ME the best game. Results may vary depending on skill levels and abilities.