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Rimonabant is the generic version of Acomplia. It is the new weight loss medication breakthrough from Sanofi-Aventis, exceeding Phentermine in it's ability to help you lose weight! It is a CB1 cannabinoid receptor antagonist, and its main avenue of effect is reduction in appetite. Rimonabant acts by obstructing the receptors, which control the food intake and energy expenditure - Thus resulting in reduced appetite.