I believe running the same play over and over again can get you kicked for excessive grieving. Which is funny, because it makes no sense to go away from a play that continues to work because your opponent is too dense to defend against it.
In Madden 13, I liked to open up all my games with the Lions by throwing a play action Go route to Calvin Johnson. If the opponent was caught unaware, it was almost always like an instant 80-yard TD.
Against one opponent, I did that on 6 consecutive drives because he continuously failed to change his defensive formation to prevent it from being open. Then I got kicked for excessive grieving.
I got kicked against my best friend once for the same thing.
It's a bit silly.