First, read my post on "
The Anatomy of a Run Play" if you haven't already. There I mention that against zone you will have chances to run between the tackles. Even against man it is possible to run between the tackles if the holes are there, but still much easier against zone.
I am assuming you won't be optioning much from under center which is fine, you don't need it. I am also assuming that you are running a pro style offense in nature. Since you are running out of I (straight-I is best, strong-I fun too) and Ace formations, I suggest your running game consists of HB Slam, HB Tackle, Dive/Iso, FB Dive, HB Sting, and Power/HB Option.
Now some College and NFL teams don't use these many concepts so rejoice! You will have a much more sophisticated run game than some of those teams. Pick and choose which ones you like or use them all. They have my stamp of approval.
HB Slam: my favorite under center run concept: It is quick hitting and the timing of the ball exchange is perfect for holes to open up when your HB gets the ball. This play allows you to take inside or outside.
HB Tackle: You might think this is a pure outside play but against zone there are opportunities to cut it back inside. Fun stuff when you do this.
HB Dive/Iso: Your HB gets the ball pretty quickly here and you don't have as much freedom to bounce it to the outside if you need you. But obviously this is meant to be ran inside. Great against a zone and against a 3-4 defense.
FB Dive: Maybe the most underrated under center run concept in 06. It is quick hitting and can taken to outside against man with possible holes opened up for you between the tackles against zone. If you don't have a decent running FB but maybe a good backup HB then use the Twin HB sub package.
HB Sting: This is similar to the HB Slam but you will only see it in your 3-wide Ace formations. It is a little more slow developing than the Slam but still effective.
Power/HB Option: Now I just told you that you don't need any option stuff but you can you the basic power/HB option as a toss play. I will cover this in my next post so watch out for it. Basically once you QB start running with your HB after his 240 degree turn or his big step back (depending on the option play) then pitch it immediately.
Don't worry if you don't understand this now. Hopefully my post on this, along with some images, will describe this easier.
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With regards to recruiting the OLine, I always get the biggest, tallest, strongest guys I can find. Size does matter in 06 unlike the PS3/360 games. I once created a DE with a 99 in everything but I made him the smallest guy you can create. I threw him in practice mode and he couldn't do anything against my OLine because he was so small. So find the biggest maulers you can find.
How do you like to use your tight ends in your offense? You can go different ways with them in terms of recruiting. These guys are very important to your run game, especially with what you are trying to do.
I hope this helps and please, you can comment on my site. It helps everyone if we can get a good discussion going on there.