I've played the game enough now to establish some of the bigger flaws. Even with sliders adjustments, the CPU QB Completion % is horrible. Always in the low 50% range for me. We all know this is untrue, as some QB's can be up around 70% (Brian Greise of the Buccaneers was 69.5% or something).
The only is the way for the CPU to make up for those lost passing yards on deep throw completions. I believe this has to do with the safeties reading the CPU's vision cone and reacting too much to it, therefore putting them out of position for a long throw.
Both of these flaws (I have CPU QB Acc. to 20 on All-Pro) are nearly gamebreaking for me, as I want to get the most realistic stats possible (and 300 yards on 7 of 21 passing isn't too real...).
If anyone has any tips as to how to get higher CPU Completion %'s, I'm all ears.