Funny you ask this ... I have found when playing the CPU, it is harder to run. I find I have to sometimes set the defense up first. On the 360, I didn't have trouble running.
Maybe it is in my head? ... but none the less, I think the running game in the PS3 version is more difficult ... IMO.
By the way, loving my PS3 ... should have gone with Sony in the first place, after all the B.S. security lockdowns MS is putting on the 360. And this is from a huge XBoxer last - gen.