Are you reading the correct defensive end? The weakside end is the one you read (the one that is not covered up by the TE). If he colapses in then you keep it and run to the area he vacates. If the end comes straight up the field then you hand off. If they are in a 3-4 scheme then you treat one of the OLB as a DL. run motion and see if they overload to one side.