It depends on what you like to do, and the type of offense you like. If you like the spread, WVU is probably your best bet since Pat White and Noel Devine are so fast. If you like the triple option, its Navy or Georgia Tech. If you like pro-style, wisconsin seems to be the most pro-style your going to find in this game. If you like an offense thats balanced between spread and pro-style, Miami (Fl) is very good. If you like the pass spread, then Texas Tech is probably the way to go. I have dynasties with Michigan, Army, Miami, Cincy and Texas Tech. So , as you can see, I really like the spread offense.
I dont use custom sliders, because I havent found any that I like and that make the gameplay more realistic.