Every game offers a variety so if you try these, don't judge off one game alone. Some games I find my offense much stronger than others, while other games end up being a real defensive battle (most of my games end up being more defensive, but that's mostly due to my style of play). Obviously the opponent has something to do with this, but the game really does offer a variety of outcomes.
I want playing with strong teams to feel "easier", while playing with weak or average teams should require more effort to pull off a win (as it should be). Don't let the low QB ACC setting for humans fool you, if you play smart you will still have a very successful passing game, although it will be much harder with lower rated QB ... again, as it should be. Throwing on the run, or while back-pedaling will definitely give you some errant throws, while setting up properly will provide some very accurate throws (even deep balls). Just make sure you have your pass plays planned out and know your progressions.
Speed: SLOW/55
Hardcore
11 min, 15 sec runoff
HUMAN / CPU
PASS OFFENSE
QB ACC ... 10 / 44
PS BLK .... 50 / 28
WR CTH ... 35 / 44 (human between 35-40)
RUN OFFENSE
BRK TKL ... 32 / 40
RN BLK ..... 38 / 98
FUM ........ 30 / 30 ... (increased due to excessive fumbles post-patch)
PASS DEFENSE
RE-TIME ... 24 / 70
INT .......... 4 / 40 (human could go higher, but you risk excessive int's)
PS RUSH ... 64 / 40
RUN DEFENSE
RE-TIME ... 12 / 54 (keep between 10-15 for human team)
SHED ... 10 / 48
TKL ......... 50 / 48
SP TEAM
FG POW 48
FG ACC 48
PT POW 48
PT ACC 40
KO POW 43
Penalties: All 100, except Holding 52, Facemask 54, Clipping 73
Sub out/in: default
Fatigue: 54 ... keep between 50-58
Injury: default
NOTE: I really haven't messed with subs or injury that much so if you have personal settings go with that.

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