If your starters are healthy a still not fatigued, they will still appear in the game as they are fit enough to play and that is due to su in and outs!!! it doesn't matter if you re-arrange your depth chart, you have to do it at the main menu before the start of the game, I cant change my depth chart mid game!!!
So try Play Fatigue 100 injuries 100!!!
For sub in/outs try these, credit goes to Jukeman.
Offense
QB- 0/1
RB- 45/60
WR- 45/60
FB/TE- 15/20
OL- 0/1
Defense
DT- 60/80
DE- 60/80
LB- 30/40
CB- 30/40
S- 15/20
my complete slider setting seem to work well and my 2nd string are always coming in and of the game, even after long drives in the 1st Q, THey seem to get a lot of game time!!
http://www.operationsports.com/forum...d-sliders.html
as for the second question I cant help you there sorry, i really have no idea on that one!!!