Wow, not APF2K8, thanks for pointing that out, I was sooo confused.
While picks may happen in the NFL, it's not programmed into Madden. What you are seeing is a pathing issue with the players. If you want to pretend it's a pick, more power to you. Myself, I'd rather employ real offensive strategy to break a defensive strategy instead of depending on deficiencies in the game.
I listed several viable options, that should work. Are you saying none of the items I provided above work in Madden? None?