I pretty much tried every set of sliders out there. Theirs things I like about each one and theirs things I don't like. So I decided to mess with the sliders that provided me with the most realism without sacrificing competition from the cpu.
Gameplay Options
Skill: Heisman
Quarter Length: 7 Minutes
Game Speed: Normal
Threshold: 25
Home Field Advantage: On
Ice The Kicker: On
Game Rules
Offsides: 100
False Start: 100
Holding: 50
Facemask: 50
Off Pass Interference: 100
Def Pass Interference: 100
KR/
PR Interference: 100
Clipping: 50
Intetional Grounding: 100
Roughing The Passer: 100
Roughing The Kicker: 100
Custom AI
USER
QB Accuracy - 15/15
Pass Blocking - 5/5
WR Catching - 45/50
RB Ability - 50/50
Run Blocking - 50/55
Pass Coverage - 65/30
Pass Rush - 25/50
Interceptions - 5/5
Run Defense - 25/30
Tackling - 50/50
FG Power - 0/0
FG Accuracy - 25/50
Punt Power - 75/80
Punt Accuracy - 70/85
Kickoff Power - 45/45
I use these in my OD and it has produced some great results. Some changes for those who think its too easy to pass deep while the QBs are too inaccurate short would be to raise human QB accuracy to 25 and raise CPU pass coverage to 45. I like these sliders and for anyone who hasn't settled on a set of sliders yet give these a try, you might enjoy them too.