More important than physics and spin is
pass trajectory.
Passes in Madden do not travel in a realistic arc.
It is either a straight line pass or a moonball.
This is why you see so many "superman swats" by LBs over the middle: the ball doesn't arc over them like it should; it travels in a straight line.
Watch this video for a good look at how a real NFL QB arches the ball up then down to his target:
Throws in Madden look more like the straight arrow coming out of the archer's bow.