Halladay is ridiculous to face. Just came across him for the first time, and all his pitches break and drop like halfway across the plate.
I managed to finally get two runs off him in the 6th and 7th innings before the CPU pulled him due to fatigue.
The elite CPU batters will also punish you hard if you leave weak pitches hanging around. Jayson Werth and Ryan Howard have owned me the last two series with Washington and Philly. Don't be afraid to walk the big hitters!
And yeah, these settings are the way to go if you want a realistic, challenging hitting experience: