I am going to start my slider set and testing again for this years version starting with speed threshold testing. This is a placeholder for where I will edit in the sliders:
Difficulty: All-american (default game setting, speed testing shows statistic cheats for heisman and varsity, also the run glitch helps the human on varsity and helps the CPU on heismann this really is the only balanced mode)
Speed threshold: 50 (appears to be correct this year)
Game speed: Normal
Quarter length: 9-11 minutes (there should be 130-150 plays total per game, about 65-70 per team; make sure you adjust for your clock managment style to get realistic statistics and yardage--I use 11)
Human/CPU
QB accuracy: 35/50
Pass blocking: 50/55 (appears to be fairly accurate, CPU needs help if you control linemen)
WR catching: 40/40 (gives 3-4 drops per game)
RB ability: 50/60 (AI access to jukes and spins, better vision esp at 60 but too many TD runs)
Run blocking: 50/55 (increases blocking on second level and big/TD runs)
Pass coverage: 40/50 (prevents sacks by giving open reciever, QBA needed for control of %)
Pass rush: 40/50
Interceptions: 35/35 (gives 1-2 per game)
Rush defense: 50/50 (effects defenders pursuit and getting off blocks)
Tackling: 40/40 (Broken tackle goal of 3-7 range, avg 4.5/game)
FG power: 45/40
FG accuracy: 30/40
Punting power: 30/45
Punting accuracy: 50/50
Kickoff power: 50/50
Penalties:
Offside: 95
False start: 100
Holding: 52
Facemask:53 (count 1 facemask penalty or RP as pass interference since that is never called)
Off PI:100 (never seen one)
Def PI:100 (never seen one)
KR/
PR Interf: 60 (never seen one)
Clipping:54
Intent grounding:100 (never seen one)
Roughing passer:60 (goal 1 per game per side to replace pass interference)
Roughing kicker:65
Autosubs (Sub out/Sub in):
Running back: 84/85 (doesn't work but next level removes in 4th quarter, use formation subs)
Coaching sliders: No changes recommended to defensive sliders only pass/run. Substitution sliders don't effect gameplay only simulation. The Pass % should be set to match the teams listed pass %. See the table at the bottom of this page.