This.
I've tried playing all-madden in past madden games and I wanted to pull my hair out in frustration.
In the passing game your WR has to be completely open with no defenders within a 5 yard radius for you to complete a pass while the CPU WRs make catches in traffic with ease.
Similarly with the running game. Their RBs will run all over you and break tonnes of tackles while your RB will be lucky to make it back to the line of scrimmage.