TakeTwo is attempting to ink an exclusive deal with the NFL once EA's deal expires (early 2014 I believe). If successful, we could possibly see a new 2k game in summer of 2014 (NFL 2K15).
However, the mere fact that TakeTwo is actively moving in, is reason enough for EA to renew the deal. Regardless, we'll see. Hopefully, we won't ever see another exclusive deal again. Competition is a good thing, seriously.