Currently, the guide is not complete in regards to storyline players. We are still doing research and in fact are asking for our guide users to assist if possible. We have some theories so far as to when (ie, what point in the CC) the storyline arcs are determined, among other aspects, but will hold off on discussing them until we have some more information.
If a storyline player dropped out of the draft, that did not affect any of the other players in the draft that we're aware of (other than a pick or two difference in projection), so there would be no reason to reload.
We noted the players' projected draft positions in stage 7 of the offseason (right before the draft). Again, only storyline players will change, as stated in the guide, and that info (for storyline players) cannot be relied on to be accurate until we know most or all of the story arcs.
-rdm