I started this set in Play Now and used it in my CCM (was using default All-Pro) once I was happy with them. The only difference I saw was the CPU run game. It wasn't really the blocking or block shed, the HB just never runs foward. Even on dives and draws, they would juke or spin to the outside. I increased the run block up to 50 and it works well now. I still saw tackle for loss and all. I haven't tried for every team though. With the Cowboys I gave up tons of yardage then a lot of tackle for loss but with the Dolphins, it was more 3-4 yards at a time.
I wouldn't say CCM is broken or anything, I believe it has something to do with the schemes that make gameplay different (and maybe teams not running by their gameplan), but that's my conspiracy.