See, that's where things have been different for me. I'm an NCAA regular and have barely won 50% of my games, usually using a much better team than the CPU. I call zone, cover 2, pretty much everything in the playbook and have noticed several plays where calling a zone was very effective.
One thing I'll also say, is that I'm using the Zoom Camera. It makes the game surprisingly difficult from a passing point of view. You have to rely on your instincts and your ability to read the defense more than ever.