I have multiple files. I have ones I play every game on and ones I sim. I turn injuries off for the simmed ones because of the frequent injuries that occur. I usually have three I play on the go with varying settings for each one. One might be all rookies and the other might be all players over 35.
With the patched GM mode, it's almost as much fun as NHL 12 now. The draft sucks though. There are no gems in later rounds anymore.
I even find myself plugging in NHL 12 some days just for the depth of its GM mode and prospects....