I have to say, I have adjusted Reaction time and tested outside runs, and I have not seen much of a change as to how well a RB gets to the outside...This may be an issue in regards to Speed Threshold?
Willingness to throw deep seems to be determined by how long it takes a receiver to get open, so lower pass cover helps; the QB accuracy itself does not seem to affect the chances of throwing deep; but WR catch may determine how tight of coverage a QB will throw into....WR Catch seems to affect separation ability, so adjusting WR catch with Pass cover may be important in finding a fair balance.