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A lot has to do with how other sliders are set as there are many sliders that are interdependent....

As it seems to be - Pass Reaction determines how well the defense reacts to the pass. The apparent trick is, anything above 50 and the defense reacts faster to the pass, but slower to the run...and then, anything lower than 50 and the defense reacts faster to the run and slower to the pass...

Pass cover appears to deal with just how well defenders will cover their opponent..This slider seems to affect defenders to where some player ratings may be artificially adjusted, making better defenders out of players who are not that great, the higher the slider goes.

Therefore, in theory, the lower you go the more the ratings of the defender matter because there is less modification applied by the slider. I have run PC on zero and good defenders still cover good, but bad defenders do not cover well as often....

As far as I understand it, a player rating, even a low rating, will allow a player to be successful over another player, who is generally better, some of the time...Your odds are just lower by how low your ratings are in comparison to the opponent your facing...

Madden is really nothing but a dice based game like Dungeons & Dragons, with modifiers and bonuses or minuses to the base dice roll...So it's all odds based, out of 100...A player with a higher number in a rating just has a better chance of winning, not a guarantee to be better all the time...