You can press triangle (PS4) and do global pass coverage adjustments for inside and outside, press, cushion, over the top, underneath and protect the sticks , man align, etc
Then you have individual adjustments which I discussed with shading individual WR's
You have to pick your poison because just like IRL you have seconds to make reads and adjustments.
Also go into the skills trainer and learn about coverages and defense. Learn what pass plays exploit which coverages and if you know that then you know not to call 2 deep coverage when you think they are going to go down the middle.
The game does make you play with real football strategy this year more than ever before.
Hats off to Rex and his team. M16 is the truth.