You can get two different break angles on the same pitch just by stepping off the rubber and selecting it again.
I see this a lot on curves. One 12-6 goes straight down, another look more like an 11 to 5 (or 1 to 7) curve.
Pitcher isn't tired or close. It could be the first two pitches of the game.
Forkballs, sliders, slurves have similar behavior.