Been playing the show since about '08. I usually play on Hall of Fame, but this year's game seemed a bit easier and so I play on Legend with my own sliders (posted in the slider forum). Closest I've come to a no no or perfecto was a one hitter, but today I finally got the no no.
Was using CC Sabathia against the Rays, who had been struggling to a 4-9 record with a mid-4 ERA. Had a perfecto into the eighth inning but I beaned the first batter, Kiermeyer. He then stole second. Next batter hit a fielders choice, moving the runner to third. I then intentionally walked Longoria but Sousa hit another fielders choice, scoring the run without the benefit of a hit. I got out of it and finished it off. Here's a few screenshots.