1. Fumbles - 0 equals most fumbles, 100 least
2. Interceptions - 0 equals least INTs, 100 most
3. Pass D Reaction - affects how quickly defenders react when your QB starts to throw the ball. Too high and they'll start closing on the ball the moment you press the button. Too low and they won't react to the ball until the WR has nearly caught it. Some people think lower Pass D Reaction time makes running tougher, I can't verify that.
4. Tackles - 100 equals best tacklers. I also am pretty positive this affects block shedding & pursuit angles.