Guys are using a variety of sets. Flazko and I went back to all-pro. Others are sticking with his all-madden sets. It depends what you like. I posted a pretty killer all-pro set a few pages back. It's 90 parity, fast game speed and the sliders are heavily weighted toward the CPU. I play 15 min/ 12 sec quarters with it, get 130 plays a game and still have low scoring games. It's a lot of fun.
All-pro 50 for everything, 50 parity and Normal speed also seems to be a good way to go if you're interested in using all-pro. It all depends on what you're looking for.