Honestly....I just don't know....I
think I know...then I wonder (I've struggled with this to be honest..TDawg just "locks and loads" and it seems to be fine). Just start right away....if you see any persistent warping or anything, then exit out and restart. Really seems to be the biggest issue in the first game after loading a slider set the first time.
Don't be like me, don't obsess over this