I have some other explanations on page 978, but this is the neater version I suppose. The penalties I believe I finally have perfect. Feels like a real game as far as that is concerned. One other thing I've found out is pass blocking does have some affect on run blocking.
All-Madden
NORMAL
8 or 10 Minutes
Accelerated clock and minimum clock time both off
Ball carrier move set to assist
Defensive assists all on
HUMAN/CPU
QB: 10/8
Pass Block: 40/36
WR: 80/72 (Cuts down on WR drops while being hit)
Run Block: 68/63 (CPU has better run blocking than Human)
Fumbles: 58/58
Pass D Reac.: 14/100 (Helps defeat the automatic win for Human WRs in man press coverage)
Interceptions: 48/45 (Helps with low interception stats)
Pass Cov: 84/100 (Same expalanation as Reaction Time)
Tackling: 45/44
FG Power: 50
FG Acc: 75
Punt Power: 50
Punt Acc: 98 (The kicking meter really hurts coffin punting. Which is why this is where it's at)
KO Power: 50
Fatigue 55
Threshold 95
Offside: 50
False Start: 16 (Was having too many, had to lower this)
Holding: 48
D Holding: 58
Face Mask: 50
D PI: 60
All other penalties on with illegal block in back and roughing the passer at 50.