I'm not holding out much hope, but for sure a revamped, more detailed and manually editable injury system is at or near the top of my wish list, as it has been for a while , the game has been sadly lacking in this respect for many years
The NFL is so much a "war of attrition" and Madden just doesn't convey this at all well
Maybe the problem is that it inherently crosses the line between gameplay ( in game injuries being more realistically portrayed) and franchise ( the mechanisms and systems to deal with them) ,with neither team willing to invest resources into improvement until the other team is in a position to also make the necessary push