Changing routes in a no huddle situation is unrealistic. Real NFL teams have simple code numbers or words for no huddle plays, the qb yells it out as they get to the line, and the ball is snapped ASAP.
In fact “hot routes” as done in Madden is rarely done in the NFL. Usually they are built in the play, and furthermore, a hot route isn’t just a changing of a route. It’s a hot read in the case of a blitz. I.e., your running back runs a rail route if the OLB blitzes and the qb immediately throws there.
There are instances where qbs will change the PLAY at the line, or call a modifier, but changing individual routes at the line? That’s as rare as a Marino fake spike.