I do believe they nerfed All Madden a bit. Trust me though if you play enough games you’ll be able to tell you’re playing a harder difficulty.
Auto subs take effect for the cpu if entered in the main menu I believe, but I haven’t tested myself.
I’m having good games using the All Madden set. My Steelers team is 94-95 overall though in year 2. I’m thinking about raising injuries to 20-25 and 50-55 when I sim because they’re just not a factor. Year 1 I had 3 “out” injuries total and never played a team with more than 2. Year 2 I’ve had 0 through 10 weeks. Makes me very nervous but I want to see some rookies play, my team and the cpu.