I agree about Eagles Run D. There was only a few games where they were actually gashed on the ground. Lions, Texans, Commanders loss, Packers, and Justin Fields, other than that, they haven't had issues with the run defense. Part of that is that they have gotten decent leads in a lot of games
I would put Bosa over Mailata rather than Johnson. Johnson still dealing with that groin injury, he still had a great game
I wouldn't just say struggle in the first half, they can't be overly cautious with Purdy. It felt in the first half, they would've rather win the game with the run game and have Purdy manage the game. I would try to attack Eagles zone Defense and put a heavy emphasis on Debo and Kittle and see if Eagles tackling holds up
I can see the Eagles Defense focusing on stopping the run and forcing Purdy to beat them through the air. I think one of the biggest matchups of the game will be Reddick vs McGlinchey. Reddick has been a terrific signing. He really has outperformed his contract. He can wreck a game if the OT can't hold up.
While I'm going with the Eagles to win, 49ers could definitely win. Obviously getting turnovers should help. But besides that, 49ers need to get to a fast start and control the game. They need long sustaining drives and stay out of obvious passing situations. For their Defense, get pressure and limit splash plays