I'm running a 7800GT. I went from a single-core 3200+ & 6800GT to my 3800+ dual-core & 7800GT. New motherboard was in the works as well. Other parts include 1GB of PC3200, X-Fi Platinum card, nothing else really too special. The controller being used is a wireless Rumblepad 2.
I wish I could figure this out, I'd really like to play some football right now. I haven't done any troubleshooting besides reinstalling the game, because I just don't know where to start. I've had this same issue on multiple revisions of Forceware video drivers, so that's not it. I haven't upgraded any motherboard drivers, maybe that's where I'll turn next.