There are never rewards without the risks.
I'm talking about the playoffs here. Is your No. 1 ace too tired to play on three days rest? Even if he is, don't pay attention to his stamina bar. You're in it to win it once you reach the fall season, so five or six good innings from your top-of-the-rotation guy is better than seven innings of mediocrity. But remember, the risk is that you're pitcher will have a terrible outing and lose the series for you. It's a big risk, but if you've mastered the art of your top pitcher, do it.
What are some other risks you've taken in an MLB 12: The Show franchise??