Well I did so many tests with these sliders (many 10 year sims and 20 year sims) that I can tell you by at least a player rating stand point everything stays pretty consistent with the out of the box ratings. I didn't play any games after any sims so I can't 100% say how the game still plays but I can't imagine it would be much different. I also did a 10 sims of 10 years to test out stats and they worked out well too. It's all in the OP if you want to check them out.
I'm currently in year 6 of my Saints cfm and nothing is out of the ordinary. I do suggest just letting the cpu auto progress your players though because no matter what you will be able to progress better then the cpu because you have a brain lol. Hope that helps.