Yes
There are two Different Team Strategy Sliders for both Human and CPU Teams. I always set those strategy sliders before I start each game. You can set the CPU's Fast Break Slider to 1 which is the lowest and it helps a little. Also set your team strategy to 1 so that your players get back after a missed shot.
Don't be afraid to boost up the Pistons Entire starting 5 Defensive Awareness to about 90 also because EA kinda screwed most of them accept Ben Wallace.
And finally after you adjust your players speed and quickness check out the lower GameSpeed around 45-50 and see if that helps you better on defense aswell.