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Old 05-14-2013, 02:03 AM   #1
Edward64
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Angelina Jolie - double mastectomy

I do admire her being pro-active and I'm not sure I could do the same in her situation. On the other hand, statistics could lie or not provide the whole context -- maybe there were other factors that contributed the the 87% risk like diet etc.

I guess if she can sleep easier at nights, good for her.

Angelina Jolie undergoes double mastectomy - CNN.com
Quote:
Actress Angelina Jolie announced in a New York Times op-ed article on Tuesday that she underwent a preventive double mastectomy after learning she carries the BRCA1 gene, which sharply increases her risk of developing breast cancer and ovarian cancer.

"My doctors estimated that I had an 87 percent risk of breast cancer and a 50 percent risk of ovarian cancer, although the risk is different in the case of each woman," Jolie wrote. "Once I knew that this was my reality, I decided to be proactive and to minimize the risk as much I could. I made a decision to have a preventive double mastectomy."

Jolie's mother Marcheline Bertrand died of breast cancer in 2007 at the age of 56.

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Old 05-14-2013, 07:40 AM   #2
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I think it's pretty courageous myself.
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Old 05-14-2013, 08:23 AM   #3
DaddyTorgo
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Good on her if it'll make her sleep better at night and all.

Have to confess my first thought when I saw this was that it was a troll-title.
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Old 05-14-2013, 08:44 AM   #4
JonInMiddleGA
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Honestly though, given her penchant for crazy, my first thought was that she probably did it to make some sort of statement or just for the hell of it. And even now, tbh, I'm not sure I buy a figure so specific as 87 percent as having come from a doctor.
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Old 05-14-2013, 09:52 AM   #5
miked
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There was a recent study in PLoS that showed a pretty strong correlation between BRCA mutations and ovarian/breast cancers, that was dependent on where the mutation was. First off, they examined nearly 12,000 patients and about 60% of these had breast or ovarian cancer (that is pretty darn strong association). They estimated the top 5% risk rate was between 81-100% depending on where the mutation was, as well as family history. Given that her mother died young of cancer, and the ability of the (very expensive) test to determine the exact mutation, 87% is highly plausible.

But she is still crazy, just not about this. It's becoming quite common for women to undergo preventative mastectomy and I believe in a few years the tests (and this procedure) will be more common and likely covered by insurance. Would the insurer rather pay 5-10k for an outpatient surgery, or have 5-10 years of chemo/radiation/surgery.
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Old 05-14-2013, 09:58 AM   #6
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Not a fan of hers in general, but this seems like a smart move given the info available. A lot of actresses would probably be to vain to do this.
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Old 05-14-2013, 10:03 AM   #7
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Seems like the right thing to do on her part, but I guess that means there won't be a Gia 2?
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Old 05-14-2013, 11:04 AM   #8
korme
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Christina Applegate had the same thing done in '08.
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Old 05-14-2013, 11:07 AM   #9
DaddyTorgo
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Seems like the right thing to do on her part, but I guess that means there won't be a Gia 2?

She's got plenty of money...I'm sure if she wants to have some work done she can have some work done...right?
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Old 05-14-2013, 11:10 AM   #10
JonInMiddleGA
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Originally Posted by miked View Post
87% is highly plausible.

Note, I don't doubt the correlation is high. I'm doubting that a doctor would have given one that specific (as opposed to something like "about 85%").
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Old 05-14-2013, 02:09 PM   #11
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Note, I don't doubt the correlation is high. I'm doubting that a doctor would have given one that specific (as opposed to something like "about 85%").

No, I think for someone who can afford a high-end doctor, these sort of numbers are typical. This sort of exact risk analysis is the cutting edge of medicine now. In particular with breast cancer they know quite a lot about how to determine a person's exact risk. Look too at Sergey Brin who has been doing a lot with his personal Parkinson's risk based on his genetics, family history, lifestyle, etc. That's a much wider range of percentage, but with breast cancer they've been able to narrow things down much more.

And yes, these preventative double mastectomies have become quite a thing. We're doing a project around that at work right now. There's been a lot of celebrity endorsement, to the point that some women are feeling pressured to go that direction. What people need to remember is that numbers like 87% are highly personal and would be completely different for another woman with breast cancer.
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Old 05-14-2013, 03:21 PM   #12
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She's got plenty of money...I'm sure if she wants to have some work done she can have some work done...right?

Apparently most insurances, including medicaid from what Ive read, cover full reconstruction in the case of double mastectomy. Either way shes already had reconstruction done.
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Old 08-03-2015, 11:48 PM   #13
B & B
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Well, this isn't me.

Crazy to think Ive been on FOFC for almost 15 years.
Fuck. Im not even starting a new thread. This just sucks.

Never crying for sympathy, but my mother who is a breast cancer Survivor from the 90s, just had another annual mammogram and tested + for cancer again.


She tested + for the BRCA same as Angelina Jolie(that whole thing was another ordeal and a 4k test) which is fairly rare , and given options.

3 weeks ago she went thru double mastectomy, when asked about the reconstruction she laughed and said , lets concentrate on getting rid of cancer first.

After successfully going thru chemo in the early 90s , and after going thru the double mastectomy the doctors came back and said that the cancer they took from the lymph nodes was 'aggressive" and they needed to start another round of chemotherapy.

They just did an "Echo" heart check to make sure she was even strong enough to go thru this. I know that's standard, but my mother is the STRONGEST person Ive ever met.

I really don't have the words. Fuck Cancer.
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Old 08-04-2015, 12:20 AM   #14
thesloppy
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That's horrible. I'm so sorry.
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Old 08-04-2015, 08:33 AM   #15
Kodos
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That's awful. Very sorry to hear about your Mom. Hopefully she can use all that strength and fight her way past the cancer.
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Old 08-04-2015, 10:19 AM   #16
BillJasper
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Originally Posted by B & B View Post
Well, this isn't me.

Crazy to think Ive been on FOFC for almost 15 years.
Fuck. Im not even starting a new thread. This just sucks.

Never crying for sympathy, but my mother who is a breast cancer Survivor from the 90s, just had another annual mammogram and tested + for cancer again.


She tested + for the BRCA same as Angelina Jolie(that whole thing was another ordeal and a 4k test) which is fairly rare , and given options.

3 weeks ago she went thru double mastectomy, when asked about the reconstruction she laughed and said , lets concentrate on getting rid of cancer first.

After successfully going thru chemo in the early 90s , and after going thru the double mastectomy the doctors came back and said that the cancer they took from the lymph nodes was 'aggressive" and they needed to start another round of chemotherapy.

They just did an "Echo" heart check to make sure she was even strong enough to go thru this. I know that's standard, but my mother is the STRONGEST person Ive ever met.

I really don't have the words. Fuck Cancer.



My thoughts are with her.
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