I suggest with any set of sliders that you take what others post as a base, then make your own adjustments based on your skill. And because the only slider in this game that seem to be universal on agreement is the Solid Hits slider. Hope this helps.
USER
Contact: 2
Power: 3
Timing: 2
Fouls: 5
Solid Hits: 0
Starter Stamina: 5
Reliever Stamina: 1
Pitcher Control: 6
Pitcher Consistency: 5
CPU
Contact: 5
Power: 5
Timing: 5
Fouls: 5
Solid Hits: 0
Starter Stamina: 5
Reliever Stamina: 1
Pitcher Control: 8
Pitcher Consistency: 8
Strike Frequency: 2
Manager Hook: 5
Pickoffs: 3
GLOBAL
Pitch Speed: 3
Fielding Errors: 5
Throwing Errors: 5
Fielder Run Speed: 1
Fielder Reaction: 10
Fielder Arm Strength: 5
Baserunner Speed: 5
Baserunner Steal Ability: 5
Baserunner Steal Frequency: 10
Wind: 5
Injury Frequency: 6 For Games I play - 0 For CPU Teams Simmed Games
Profile/Global SETTINGS:
Warm Up Pitchers: OFF
Hitting Difficulty: All-Star
Pitching Difficulty: All-Star
Pitch Interface: Meter
Guess Pitch: Off
Strike Zone: OFF
Hot Zones: OFF
Pitching Ball Marker: Fade
Auto Throwing: OFF
Auto Baserunning: Assist
Fielding Assist: Manual
Auto Sliding: Assist
Pitch Callout: Full
Tag Up Indicator: ON
Catch Region Indicator: ON
Catch Position Indicator: ON
Fielding View Offense: Medium
Fielding View Defense: Medium
Batting View: Catcher
Pitching View: Pitcher
Runner Windows: ON
Baserunning Control: Default
Swing Influence: ON
Pitch Repertoire: Real Life
Pitch Confidence: ON
Plate Coverage Indicator: OFF
Swing/Pitch Indicator: ON
Rob HR Indicator: ON
Vibration: ON
API: Default
Umpire Appeals: On