couple of questions:
which roster are you using? SF is using original rosters and i am using the downloaded last regular season official roster from jan or feb. if you are using edited these will probably need personal tweaking on your part.
second, are you running and blocking at 18 or lower? if you lower it, you will find it harder. i would lower human running first because blocking too low means jailbreaks for the cpu pass rush. i am not the kind to be able to chain multiple runs animations.
lastly, you may want to give them 2 or 3 games to see how the work against different teams. i hope these work for you or enable you to tweak to your liking.
how many cpu ints were there?
penalties are maxed except facemask and holding which are around 20 and clipping is 0 or 10 because of the stat bug which is really irritating to me lately.