Oh, I can get the CPU to run the ball quite well against me in short bursts and occassional long runs mixed in depending on whether the back is a gamebreaker. I just hate how they run. It's zig-zag nation meets herky-jerkyville. It just looks awful.
I never switch on D after the ball is snapped and don't use any of the "Run Right", "Run Middle" pre-snap stuff.
My three main gripes with the running game and pretty much the game (in no particular order):
1) CPU running animations and lack of fluidity. Hit a freaking hole. Make a move and run straight ahead. Not zig-zag or parallel to the endzone. STRAIGHT ahead.
2) Run blocking slider is broken because it has too much of an impact on KRs. Silliness.
3) CPU Dual Threat QBs. Make me fear them. I want to stress playing against a Griffen III, Pryor, Tebow or McCoy. Right now. I don't at all.
I am still loving this game more than any other NCAA though.